PHAR 7632 Spring 1999

Biopharmaceutics

OU HSC College of Pharmacy

First Semester Exam - Answers

18 February 1999

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Section TWO. True/False Check the Correct Response. 10 x 2 = 20 points

Q 2.1 The value of e-0.58 is 1.786.

False - e0.58 is 1.786

Q 2.2 Detectors used for quantitation with the HPLC method include electron capture and flame ionization.

False - GLC detectors

Q 2.3 The EMIT assay method involves quantitation using the measurement of radioactivity associated with the bound drug fraction.

False - Enzyme Reaction

Q 2.4 The point-slope method can be used to numerically integrate differential equations.

True

Q 2.5 The Laplace transform technique can be used to numerically integrate differential equations.

False - Analytical Integration

Q 2.6 The Laplace of a constant is the constant divided by s.

True

Q 2.7 Boomer can be used to calculate concentration versus time data using given parameter values or to find best values for parameters.

True

Q 2.8 When a substance emits light by fluorescence it is usually at the same wavelength as the excitation wavelength.

False - Wavelength is higher (lower energy)

Q 2.9 Spreadsheets are useful for calculating and graphing various equations related to pharmacokinetics.

True

Q 2.10 UV-visible absorption spectra exhibit sharp peaks because the absorption of light involves only electronic transitions and no transfer of energy via rotation or vibration.

False - broad peaks because of rotation and vibration

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