Section ONE. Sketch a Graph or Diagram - Sketch the graphs or diagrams requested in the space provided. Include any distinguishing characteristics. Assume that a linear one compartment model applies unless otherwise specified. Include labels and units. 4 x 4 = 16 points

Q 1.1 Sketch the components of the HPLC assay method. Label three components.

Diagram

Q 1.2 Semi-log plot of Cp versus time after an IV Bolus Dose.

Plot

Q 1.3 Following a successful fitting of a model to a set of data a plot of Observed versus Calculated data was prepared. Sketch this graph.

Plot

The data weren't defined in this question so units aren't required unless you specify Cp etc.

Q 1.4 A linear plot of ΔCp/Δt versus Cp for a first order plot.

Plot

Note: The zero point is at the top of the graph and needs to be specified.