PHAR 7632 Spring 1999

Biopharmaceutics

OU HSC College of Pharmacy

Final Exam 5 May 1999 - Answers - Section 3 Q1

Section THREE Calculations This section = 15 + 25 + 10 + 10 = 60 points

Show all your work for full credit. All material not deleted or crossed-out will be considered for grading. Put labels and units on all graphs.

Q 3.1 (15 points) Derive the integrated equation for M2 in the following model after an IV bolus dose using the Laplace transform method.

ROOTS = -kel and -kmu2