PHAR 7632 and PHAR 7633
Pharmacokinetics and Biopharmaceutics
This is a two course sequence which includes not only pharmacokinetics and biopharmaceutics but also pharmaceutical analysis and mathematical modeling. Pharmacokinetics is the mathematical description of drug absorption, distribution, metabolism and excretion. Biopharmaceutics is the study of factors which affect drug absorption, distribution, metabolism and excretion. Pharmaceutical analysis will include a variety of methods by which drug concentrations in biological matrices and formulations are determined. Mathematical modeling involves the determination of the best parameter values for models used to fit experimental data determined in pharmacokinetic studies or clinical uses of pharmacokinetics.
Student Objectives
- Derive and use the differential and integrated equations associated with drug pharmacokinetics; this includes determination of parameter values and development of drug dosage regimens
- Understand and assess factors which affect the absorption, distribution, metabolism and excretion of drugs
- Understand the techniques used to determine drug concentrations in biological and formulation matrices
- Understand and use the techniques required to mathematically model pharmacokinetic data
Instructor: David W.A. Bourne, Ph.D.
Office
CPB 303
No set office hours, drop by (not too early) or set-up a time in class or by email.
I usually keep my door open when I am in my office. You are welcome to come in and ask for help. I can usually stop what I am doing within a few minutes. If the door is closed I might be away for a few minutes only or longer. Feel free to wait for a few minutes. I might be on the phone and not able to help, usually this would only be a few minutes also. Feel free to wait for a few minutes.
E-mail Address
Instant Message (IM) Screen Name:
- boomer5321 - usually running when my computer is turned on
Free IM Client
- From AOL, the main page gives links for downloading the client and applying for a free account.
Scheduled Class Meeting Time
- Class Meeting Time (PHAR 7632): Tuesday and Thursday in CPB 103 and ID28 SAC (via video conference) at 11 am to 11:50 am
- Class Meeting Time (PHAR 7633): Monday, Wednesday, and Friday in CPB 101 at 11:00 am to 11:50 am
The class is being presented simultaneously to two classrooms (one class), one in Oklahoma City (OKC) and the other in Tulsa. I anticipate that all the classroom material will originate in Oklahoma City, CPB 103. Since I am the only instructor in PHAR 7632 and 7633 the length of classroom sessions can be flexible. There will be homework assigned, there will be outside classroom time assignments so filling a 50 minutes block of time 2 or 3 times a week is not a major objective. Most of the course content is on this web site.
Consequently:
- If a class does finish early (that is no more new material) I will usually be available to fill in the allocated time with questions and answers via video conference 'far end' (distant) or with 'near end' (local) students.
- If there is a network (or other computer) problem I will not cover new material during the downtime. If the breakdown is during the first part of the class time we may be able to get back up for the rest of the time. If the break is towards the end of class time I will probably abandon the class for new material, reverting to answering questions from local students.
- Two screens. I was going to comment that I will tend to use the west screen and essentially ignore the east screen, however, since these lectures are presented by video conference I will try to ignore both large screens in OKC and use the computer monitor or overhead to emphasize material.
- OKC Microphones. Since the sound from the microphones in OKC are output via the speakers at the front, side of the room please try to identify yourself by raising or waving your hand if you want me to see where you are sitting. It seems clumsy but you might identify where you are, that is, OKC or Tulsa.
- Attendance. There are no points awarded or penalties assessed in relation to attendance in this class. Most of the material is available via the website. If you are unable to attend class for any please ask your class colleagues for information about the material covered. If you need help understanding any material in this class please review the online material, your notes, or ask the instructor during or after class, in the instructors's office, by email or by IM (see above). Lecture material will be presented only once and will not be available by any streaming or storage medium so if you need to ask questions as the material is presented please plan to attend lectures in OKC or Tulsa. If class is cancelled or class time is changed I will try to let you know as soon as possible by email. Please ensure that I have a record of your correct email address.
Next Page
Copyright 2001-3 David W. A. Bourne (david@boomer.org)
This file was last modified:
Tuesday 01 Jul 2003 at 01:32 PM