Make Predictions

Figure 6.4.1 Dose required to achieve a certain plasma concentration

Using these data we can calculate (or predict) the drug concentrations at various time up to and including the six hours requested.

Figure 6.4.2 Plasma concentration versus time after a 65 mg IV bolus dose

We can also predict drug concentrations after a specified drug dosage regimen.

Figure 6.4.3 Concentrations after multiple IV Bolus doses

With this information we can predict drug plasma concentrations after multiple 100 mg IV bolus doses every 12 hours.

Figure 6.4.4 Linear plot of drug concentration versus time after multiple IV Bolus doses

With more extensive models even more involved predictions or calculations can be performed.

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Copyright 2001-3 David W. A. Bourne (david@boomer.org)