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Figure 8.6.1 The model is defined with Fortran statements
The xp term defines the rate of change of drug amount and the y term is the drug concentration term. Note the inclusion of P(1) and P(2) to represent kel and V. Once the program is started the user enters numerical information about the model and the dose administered.
Figure 8.6.2 Entering model and dose information
Model output specification and the data are entered next.
Figure 8.6.3 Output specification and data entry are next
Figure 8.6.4 Inputting initial parameter estimates
Refer to the ADAPT manual for more detail. ADAPT (Reference http://bmsr.usc.edu/Software/Adapt/adptmenu.html)
Copyright 2001-3 David W. A. Bourne (david@boomer.org)