| Boomer Manual and Download | ||||
| PharmPK Listserv and other PK Resources | ||||
| Previous Page | Previous Chapter | Course Index | Next Chapter | Next Page |
Larger volume, than sc, can be given by IM
A depot or sustained release effect is possible with IM injections, e.g. procaine penicillin
Disadvantages:
Trained personnel required for injections. The site of injection will influence the absorption, generally the deltoid muscle is the best site
Absorption is sometimes erratic, especially for poorly soluble drugs, e.g. diazepam, phenytoin. The solvent maybe absorbed faster than the drug causing precipitation of the drug at the site of injection.
Copyright 2001-3 David W. A. Bourne (david@boomer.org)
This file was last modified: