PHAR 7632/7633 Syllabus

Topics to be Covered in PHAR 7632 and PHAR 7633

Glossary

PHAR 7632

1. Introduction (PHAR 7632)
2. Mathematical material
3. Pharmaceutical analysis
4. Pharmacokinetics introduction
5. One compartment IV bolus
6. Modeling
7. More Laplace transforms
8. Program set-up
9. Program output evaluation
10. Numerical integration
11. Optimization
12. Analysis of urine data
13. Weighting schemes

    PHAR 7633

14. Introduction (PHAR 7633)
15. Intravenous infusion
16. Routes of drug administration
17. Pharmacokinetics of oral administration
18. Bioavailability calculations
19. Selection of the "best" model
20. Identifiability
21. Bioavailability studies
22. Physiological factors affecting oral absorption
23. Physical-Chemical factors affecting oral absorption
24. Formulation factors affecting oral absorption
25. Multiple IV bolus dose administration
26. Multiple oral dose administration
27. Routes of excretion
28. Drug metabolism
29. Drug distribution
30. Multi-compartmental pharmacokinetic models
31. Non-linear pharmacokinetic models
32. Clinical applications of pharmacokinetics
33. Optimal sampling
34. Bayesian analysis and population modeling
35. Pharmacodynamic models
36. Physiologically based pharmacokinetic models

    ---

    • Slides in PDF Format

Copyright 2001-3 David W. A. Bourne (david@boomer.org)