Chapter 5 - Page 2 - Java 1

Linear Plot of Plot of X, U, M and Mu versus Time after a Single IV Bolus Dose Administration One Compartment Model

Comments

Drug elimination by excretion as unchange drug and metabolism can be explored. Changing the parameters kel, fe and kmu provide a number of variations in the amounts excreted as drug or metabolism.

Figure 5.13.1 Diagram illustrating IV Blous Dose, One Compartment model with Excretion and Metabolism

Equation 5.13.1 Amount of Drug in the Body, X, versus time

Equation 5.13.2 Amount of Drug Excreted into Urine, U, versus time

Equation 5.13.3 Amount of Metabolite in the Body, M, versus time

Equation 5.13.4 Amount of Metabolite excreted into Urine, Mu, versus time

Explore the equation by changing the parameter(s). Add additional lines with different parameter values using the Add Line button.

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