Calculation of Drug Concentration

Uniform Multiple IV Bolus Dose Regimen

A patient is started on a drug at an IV bolus dose of 50 mg every 8 hours. Calculate the drug concentration at a few of time points during the first three dosing interval. Specifically calculate the concentration three hours after the first dose, two hours after the second dose and one hour after the third dose. Assume a one compartment linear model applies to this drug in this concentration range. The kel and V for this drug in this patient are 0.181 hr^-1 and 10.8 L, respectively.

NOTE: Clicking the button above
will prevent you getting credit for this problem

Print this page if you want, work the problems and

You will have one chance to submit your answers for this problem [# 760403433]. You can try the homework problem more than once with different data to improve your grade. Your highest score is recorded. After submitting your answers you can use the browser back arrow to get back here and see how the compuer worked the problem.

The equation:

Equation 25.2.1 Drug Concentration, Cp, after Multiple IV Bolus Doses (Uniform Dosing Interval and Dose)

Last update: Mon 27 Feb 2006 12:47:22 pm

Practice problem answers may not be available on occasion. These practice problems may be used for graded homework from time to time. For any given problem set this will probably be for one or two weeks at most. Please try later.