Timehr |
Cpmg/L |
ΔAUCmg.hr/L |
AUCmg.hr/L |
Cp • tmg.hr/L |
ΔAUMCmg.hr ^{2}/L |
AUMCmg.hr ^{2}/L |

0 | 0.924 | 0 | 0 | 0 | 0 | 0 |

0.25 | 0.533 | 0.182 | 0.182 | 0.133 | 0.0167 | 0.0167 |

0.5 | 0.341 | 0.109 | 0.291 | 0.171 | 0.038 | 0.0546 |

0.75 | 0.246 | 0.0734 | 0.365 | 0.185 | 0.0444 | 0.099 |

1 | 0.198 | A | C | 0.198 | 0.0478 | 0.147 |

1.25 | 0.173 | B | 0.467 | 0.216 | 0.0518 | 0.199 |

1.5 | 0.159 | 0.0415 | 0.508 | 0.239 | D | F |

2 | 0.145 | 0.076 | 0.584 | 0.29 | E | 0.388 |

4 | 0.12 | 0.265 | 0.849 | 0.48 | 0.77 | 1.16 |

6 | 0.1 | 0.22 | 1.07 | 0.6 | 1.08 | 2.24 |

9 | 0.0765 | 0.265 | 1.33 | 0.689 | 1.93 | 4.17 |

12 | 0.0585 | 0.203 | 1.54 | 0.702 | 2.09 | 6.26 |

24 | 0.0201 | 0.472 | 2.01 | 0.482 | 7.11 | 13.4 |

Infinity | 0 | G | H | 0 | I | J |

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**Equation 30.4.1 AUC for the segment from i-1 to i**

**Equation 30.4.2 AUC for the last segment from t _{last} to infinity**

where k' is the slowest rate constant. k' can be calculated from the terminal slope of Cp versus time on semi-log graph paper.

**Equation 30.4.3 AUMC for the last segment from t _{last} to infinity**

where k' is the slowest rate constant. k' can be calculated from the terminal slope of **Cp versus time** on semi-log graph paper.

**Equation 30.4.4 Mean Resident Time (MRT)**

**Equation 30.4.5 Clearance (CL)**

**Equation 30.4.6 Steady State Apparent Volume of Distribution, V _{ss}**

Last update: Thu 19 Jan 2012 09:10:00 am