Timehr |
Cpmg/L |
ΔAUCmg.hr/L |
AUCmg.hr/L |
Cp • tmg.hr/L |
ΔAUMCmg.hr ^{2}/L |
AUMCmg.hr ^{2}/L |

0 | 1.27 | 0 | 0 | 0 | 0 | 0 |

0.25 | 0.927 | 0.275 | 0.275 | 0.232 | 0.029 | 0.029 |

0.5 | 0.756 | 0.21 | 0.485 | 0.378 | 0.0762 | 0.105 |

0.75 | 0.663 | 0.177 | 0.662 | 0.497 | 0.109 | 0.215 |

1 | 0.608 | A | C | 0.608 | 0.138 | 0.353 |

1.25 | 0.57 | B | 0.969 | 0.713 | 0.165 | 0.518 |

1.5 | 0.541 | 0.139 | 1.11 | 0.812 | D | F |

2 | 0.493 | 0.259 | 1.37 | 0.986 | E | 1.16 |

4 | 0.35 | 0.843 | 2.21 | 1.4 | 2.39 | 3.54 |

6 | 0.249 | 0.599 | 2.81 | 1.49 | 2.89 | 6.44 |

9 | 0.15 | 0.599 | 3.41 | 1.35 | 4.27 | 10.7 |

12 | 0.0898 | 0.36 | 3.77 | 1.08 | 3.64 | 14.3 |

24 | 0.0117 | 0.609 | 4.38 | 0.281 | 8.15 | 22.5 |

Infinity | 0 | G | H | 0 | I | J |

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**Equation 30.4.1 AUC for the segment from i-1 to i**

**Equation 30.4.2 AUC for the last segment from t _{last} to infinity**

where k' is the slowest rate constant. k' can be calculated from the terminal slope of Cp versus time on semi-log graph paper.

**Equation 30.4.3 AUMC for the last segment from t _{last} to infinity**

where k' is the slowest rate constant. k' can be calculated from the terminal slope of **Cp versus time** on semi-log graph paper.

**Equation 30.4.4 Mean Resident Time (MRT)**

**Equation 30.4.5 Clearance (CL)**

**Equation 30.4.6 Steady State Apparent Volume of Distribution, V _{ss}**

Last update: Thu 19 Jan 2012 09:10:00 am