Timehr |
Cpmg/L |
ΔAUCmg.hr/L |
AUCmg.hr/L |
Cp • tmg.hr/L |
ΔAUMCmg.hr ^{2}/L |
AUMCmg.hr ^{2}/L |

0 | 1.43 | 0 | 0 | 0 | 0 | 0 |

0.25 | 0.947 | 0.297 | 0.297 | 0.237 | 0.0296 | 0.0296 |

0.5 | 0.699 | 0.206 | 0.503 | 0.35 | 0.0733 | 0.103 |

0.75 | 0.568 | 0.158 | 0.661 | 0.426 | 0.0969 | 0.2 |

1 | 0.496 | A | C | 0.496 | 0.115 | 0.315 |

1.25 | 0.455 | B | 0.913 | 0.569 | 0.133 | 0.448 |

1.5 | 0.43 | 0.111 | 1.02 | 0.645 | D | F |

2 | 0.399 | 0.207 | 1.23 | 0.798 | E | 0.961 |

4 | 0.326 | 0.725 | 1.96 | 1.3 | 2.1 | 3.06 |

6 | 0.269 | 0.595 | 2.55 | 1.61 | 2.92 | 5.98 |

9 | 0.202 | 0.707 | 3.26 | 1.82 | 5.15 | 11.1 |

12 | 0.152 | 0.531 | 3.79 | 1.82 | 5.46 | 16.6 |

24 | 0.0485 | 1.2 | 4.99 | 1.16 | 17.9 | 34.5 |

Infinity | 0 | G | H | 0 | I | J |

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**Equation 30.4.1 AUC for the segment from i-1 to i**

**Equation 30.4.2 AUC for the last segment from t _{last} to infinity**

where k' is the slowest rate constant. k' can be calculated from the terminal slope of Cp versus time on semi-log graph paper.

**Equation 30.4.3 AUMC for the last segment from t _{last} to infinity**

where k' is the slowest rate constant. k' can be calculated from the terminal slope of **Cp versus time** on semi-log graph paper.

**Equation 30.4.4 Mean Resident Time (MRT)**

**Equation 30.4.5 Clearance (CL)**

**Equation 30.4.6 Steady State Apparent Volume of Distribution, V _{ss}**

Last update: Thu 19 Jan 2012 09:10:00 am