Timehr |
Cpmg/L |
ΔAUCmg.hr/L |
AUCmg.hr/L |
Cp • tmg.hr/L |
ΔAUMCmg.hr ^{2}/L |
AUMCmg.hr ^{2}/L |

0 | 2.73 | 0 | 0 | 0 | 0 | 0 |

0.25 | 2.02 | 0.594 | 0.594 | 0.505 | 0.0631 | 0.0631 |

0.5 | 1.66 | 0.46 | 1.05 | 0.83 | 0.167 | 0.23 |

0.75 | 1.46 | 0.39 | 1.44 | 1.1 | 0.241 | 0.471 |

1 | 1.34 | A | C | 1.34 | 0.304 | 0.775 |

1.25 | 1.26 | B | 2.12 | 1.58 | 0.364 | 1.14 |

1.5 | 1.2 | 0.308 | 2.43 | 1.8 | D | F |

2 | 1.1 | 0.575 | 3 | 2.2 | E | 2.56 |

4 | 0.821 | 1.92 | 4.92 | 3.28 | 5.48 | 8.05 |

6 | 0.614 | 1.44 | 6.36 | 3.68 | 6.97 | 15 |

9 | 0.397 | 1.52 | 7.87 | 3.57 | 10.9 | 25.9 |

12 | 0.257 | 0.981 | 8.85 | 3.08 | 9.99 | 35.9 |

24 | 0.0449 | 1.81 | 10.7 | 1.08 | 25 | 60.9 |

Infinity | 0 | G | H | 0 | I | J |

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**Equation 30.4.1 AUC for the segment from i-1 to i**

**Equation 30.4.2 AUC for the last segment from t _{last} to infinity**

where k' is the slowest rate constant. k' can be calculated from the terminal slope of Cp versus time on semi-log graph paper.

**Equation 30.4.3 AUMC for the last segment from t _{last} to infinity**

where k' is the slowest rate constant. k' can be calculated from the terminal slope of **Cp versus time** on semi-log graph paper.

**Equation 30.4.4 Mean Resident Time (MRT)**

**Equation 30.4.5 Clearance (CL)**

**Equation 30.4.6 Steady State Apparent Volume of Distribution, V _{ss}**

Last update: Thu 19 Jan 2012 09:10:00 am