Timehr |
Cpmg/L |
ΔAUCmg.hr/L |
AUCmg.hr/L |
Cp • tmg.hr/L |
ΔAUMCmg.hr ^{2}/L |
AUMCmg.hr ^{2}/L |

0 | 0.827 | 0 | 0 | 0 | 0 | 0 |

0.25 | 0.588 | 0.177 | 0.177 | 0.147 | 0.0184 | 0.0184 |

0.5 | 0.459 | 0.131 | 0.308 | 0.23 | 0.0471 | 0.0654 |

0.75 | 0.388 | 0.106 | 0.414 | 0.291 | 0.0651 | 0.131 |

1 | 0.346 | A | C | 0.346 | 0.0796 | 0.21 |

1.25 | 0.319 | B | 0.589 | 0.399 | 0.0931 | 0.303 |

1.5 | 0.3 | 0.0774 | 0.666 | 0.45 | D | F |

2 | 0.273 | 0.143 | 0.809 | 0.546 | E | 0.658 |

4 | 0.201 | 0.474 | 1.28 | 0.804 | 1.35 | 2.01 |

6 | 0.149 | 0.35 | 1.63 | 0.894 | 1.7 | 3.71 |

9 | 0.0954 | 0.367 | 2 | 0.859 | 2.63 | 6.34 |

12 | 0.061 | 0.235 | 2.23 | 0.732 | 2.39 | 8.72 |

24 | 0.0102 | 0.427 | 2.66 | 0.245 | 5.86 | 14.6 |

Infinity | 0 | G | H | 0 | I | J |

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**Equation 30.4.1 AUC for the segment from i-1 to i**

**Equation 30.4.2 AUC for the last segment from t _{last} to infinity**

where k' is the slowest rate constant. k' can be calculated from the terminal slope of Cp versus time on semi-log graph paper.

**Equation 30.4.3 AUMC for the last segment from t _{last} to infinity**

where k' is the slowest rate constant. k' can be calculated from the terminal slope of **Cp versus time** on semi-log graph paper.

**Equation 30.4.4 Mean Resident Time (MRT)**

**Equation 30.4.5 Clearance (CL)**

**Equation 30.4.6 Steady State Apparent Volume of Distribution, V _{ss}**

Last update: Thu 19 Jan 2012 09:10:00 am