PharmPK Discussion - 6beta-OH-cortisol/cortisol ratio

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On 14 Sep 2007 at 16:41:06, Rostam Namdari (chista90.at.yahoo.com) sent the message


The following message was posted to: PharmPK

Dear Colleagues,
Is there any reliable
data or published literature on urinary 6beta-OH-cortisol/cortisol
ratio for
healthy men between 18-50 yr (normal range or mean +/- SD)?
Rostam

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On 25 Sep 2007 at 05:01:13, ehab eldesoky (ehegypt.at.yahoo.com) sent the message


The following message was posted to: PharmPK

Dear colleague,

Sorry for this delayed reply!.

Please review the following two papers for urinary
6beta-OH-cortisol/cortisol ratio in adults:

1- ElDesoky Ehab S, et al. Study of urinary
6beta-OH-cortisol/cortisol ratio in spot urine sample
as a biomarker of 3A4 enzyme activity in healthy and
epileptic subjects of Egyptian population.
Pharmacological Research 2005; 51: 575-580.

2- ElDesoky Ehab S, et al.Study of the urinary ratio
of urinary 6beta-OH-cortisol/cortisol as a biomarker
of cyp 3A4 activity in Egyptian patients with chronic
liver diseases. Drug Target Insights 2006; 2: 157-164.

  regards,

Professor Ehab S ELDesoky
Professor of Pharmacology
Assiut University
Assiut, Egypt.

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