PharmPK Discussion List Archive - 2010

• A question of clearance
• Allometric exponents
• Antidrug antibody
• Assay validation for tissue samples
• AUC greater than 80% of AUC(inf)
• Bioanalysis in formalin-fixed tissue
• Clavulanic acid absorption
• Concentration of DMSO DMA in injectable solution
• Confirmatory re-assay
• Dose calculation and considerations for acute toxicity studies
• HPLC column cleaning
• Human efficacious dose
• Increased volume of distribution with age
• Low bioavailability drugs list
• Method development problems
• Microsomal t1/2 of Verapamil and Piroxicam
• Pharsight Survey: End of Phase 2A Meetings with FDA-Your Input Requested
• POP_PHARM in Israel
• Protein Binding
• Sample size for BE study
• Species differences in GI tract and impact on oral %F
• Stability Validation
• Toxicity for Bioequivalent
• Vehicle formulation for dogs

Copyright 1995-2009 David W. A. Bourne (david@boomer.org)