Pharmacokinetics: Principles and Application

by Mehdi Boroujerdi

New York, NY
ISBN No. 0-07-135164-7

Contents (xx + 420 pages)

Chapter 1: Groundwork.
Chapter 2: General Introduction to Physiologic Modeling and Compartmental Analysis.
Chapter 3: Routes of Administration and Drug Absorption.
Chapter 4: Distribution of Drugs in the Body.
Chapter 5: Elimination of Drugs from the body.
Chapter 6: Linear One-compartment Model with Instantaneous Input and first-Order Output.
Chapter 7: Linear One-compartment Model with Zero-order Input and First-order Output.
Chapter 8: Linear One-compartment Model with First-order Input and First-order Output.
Chapter 9: Analysis of Urinary Data: Linear One-compartment Model.
Chapter 10: Multiple Dosing Kinetics: One-compartment Model.
Chapter 11: Multicompartment Models: Linear Two-compartment Model with Instaneous Input and first-order Disposition.
Chapter 12: Mutliple-dosing Kinetics: Two-compartment Model.
Chapter 13: Multicompartment Models: Linear Two-compartment Model with First-order Input and First-order Disposition.
Chapter 14: General Approaches to Doage Adjustment for Patients with Renal Failure.
Chapter 15: Effect of Dialysis on Pharmacokinetics of Drugs
Chapter 16: Bioavailability and Bioequivalence Evaluation.
Chapter 17: Noncompartmental Approach in Pharmacokinetics Based on Statistical Moments.
Chapter 18: Pharmacokinetic-Pharmacodynamic Modeling.
Appendix I Assignment Answers.
Appendix II Glossay of Variables and Constants.