Time hr | Concentration mg/L |
0.5 | 13.5 |
1.0 | 13.5 |
2.0 | 10 |
4.0 | 7.6 |
6.0 | 5.1 |
kel from the -ve slope of ln-linear line through the data. Note the concentration on the line at 6 hours is 5.15. NOTE:: This value and the value for Cp0 will depend on where you put the line. Everyone may put the line in a different place.
V = Dose/Cp0 = 500/15.2 = 32.9 L
Clearance = kel x V = 0.180 x 32.9 = 5.92 L/hr = 99 ml/min
Parameter | Value | Unit |
Cp0 | 15.2 | mg/L |
kel | 0.180 | hr-1 |
V | 32.9 | L |
Clearance | 5.92 | L/hr |
99 | ml/min |