Rearranging (Equation 73) gives
Thus, Dose = 15 x 23 x 0.06 x 6 / 0.9 = 145 mg. Give 150 mg to achieve a
of 15.5 mg/L
Making various assumtions (Equation 71) can be used to calculate Cpmin = (150 / 23) x (0.69 / (1 - 0.69)) = 12.8 mg/L
By rough estimation Cpmax can be calculated as 18.2 mg/L (15.5 + (15.5 - 12.8))