PHAR 4634 - Chapter 22 Page 12
Student Presentations of a Pharmacokinetic Paper
Objective
To briefly (aim for 4 minutes) present a paper or part of a paper concerning
pharmacokinetics. To clearly present the methods, results, and conclusions from
the paper. To present your conclusions or recommendations from the results of
the paper.
General Methods
Selection of paper
The topic of the paper selected should
be pharmacokinetics. That is, the paper will deal with the pharmacokinetics of
a drug (or small collection of drugs) in a group of subjects. Rather than
highlight the absorption process, this paper should deal with another aspect of
drug pharmacokinetics. Thus excretion, metabolism, or distribution may be the
emphasis of this paper.
Review your choice of paper with Dr Bourne for suitability. Once the paper
is approved you can use the on-line database to ensure that your paper has
not been chosen by someone else. You can then enter your choice
in the database
using the name and password given in class.
Topics may include:-
- Pharmacokinetic characterization of a new drug;
- Pharmacokinetic investigation of the effect of disease state (such as renal, hepatic, reduced cardiac function) or varied patient characteristic (age, sex, weight, smokers);
- Development of a dosage regimen based on pharmacokinetic principles); or
- Pharmacokinetic base drug interactions.
Journal sources could include:
- Biopharmaceutics and Drug Disposition
- British Journal of Clinical Pharmacology
- Drug Development and Industrial Pharmacy
- European Journal of Clinical Pharmacology
- International Journal of Pharmaceutics
- Journal of Clinical Pharmacokinetics
- Journal of Clinical Pharmacology
- Journal of Clinical Pharmacology and Therapeutics
- Journal of Pharmaceutical Sciences
- Journal of Pharmacokinetics and Biopharmaceutics
Preparation of presentation aids
This will usually be computer presentations or overhead slides. These are not essential but generally will help. You may put some material on the chalk board during a break and then give your presentation after the break. The computer presentation or overhead (or board material) will be better if you don't try to put to much on a single slide/overhead. Generally the figures and tables in a publication will be too small for effective presentation as direct photocopy. It will be better if you can carefully draw (by hand) the figure or table or list of conditions, etc. on each overhead. This will also allow you to select the important material to present as you should limit the number of overheads used.
General Suggestions from practice presentations
- Practice your presentation or at least read through it a few times
- Don't give too much detail, be selective, give the important information. Your ability to select the important material will be assessed.
- Ask ahead of time if you don't understand something you are going to present. Don't present things you don't understand.
- No need to highlight class material, unless it allows you to summarize
- Keep to time if possible, presentations which are too long (greater than 5 minutes) or too short (less than 3 minutes) will loose some points.
- Don't read all the details from the overhead, refer to the overhead.
Grading Scheme
Introduction
|
2
|
Good start, aims defined, background
|
Methods
|
3
|
Clearly presented, important details, too much detail
|
Results
|
3
|
Clearly presented, appropriate, too much detail
|
Conclusions
|
3
|
Clearly presented, material understood
|
Questions
|
2
|
Understood, answered well
|
General presentation
|
3
|
Quality and use of aids, transitions, technique, confidence
|
Appropriateness of material
|
2
|
Meet guidelines, too extensive (review?)
|
Timing
|
2
|
Too long (greater 5 minutes), too short (less than 3 minutes)
|
Total
|
20
|
equals 5% of grade
|
This page was last modified: 12 February 2001
Copyright 2001 David W.A. Bourne