Section ONE Sketch a Graph or Diagram&emdash;Sketch the graphs or diagrams requested in the space provided. Make sure you carefully include any distinguishing characteristics and include labels andunits for all graph axes. Assume that a linear onecompartment model applies for each sketch when appropriate. 5 x 4 = 20 points
Q 1.1 Version A. A linear plot of Cp versus time after four equal multiple IV bolus doses given at intervals equal to the drug elimination halflife. 

Q 1.1 Version B, D. A semilog plot of Cp versus time after four equal multiple IV bolus doses given at intervals equal to the drug elimination halflife. 

Q 1.1 Version C. A linear plot of Cp versus time after four equal multiple oral doses given at intervals equal to the drug elimination halflife. 

Q1.2 Version A. A Dettli plot for a drug with fe = 0.25. 

Q1.2 Version B. A Dettli plot for a drug with fe = 0.75. 

Q1.2 Version C. A Dettli plot for a drug with fe = 0.0. 

Q1.2 Version D. A Dettli plot for a drug with fe = 1.0. 

Q1.3 Version A, C, D. A Scatchard plot representing 1:1 drug protein binding with one type of binding site. 

Q1.3 Version B. Q1.4 Version D. Draw a diagram representing enterohepatic recycling and label three components.. 

Q1.4 Version A, D. Q1.5 Version B. Sketch a nephron and label three components 

Q1.4 Version B. Sketch an equilbrium dialysis experiment for protein binding determination and label the components. 

Q1.4 Version C. Sketch an ultrafiltration experiment for protein binding determination and label the components. 

Q1.5 Version A, C. Sketch a linear plot of Cp versus time after a single oral dose illustrating enterohepatic recycling. 
