Boomer Manual and Download
PharmPK Listserv and other PK Resources
Previous Page Course Index Next Page

Numerical Integration

Student Objectives for this Chapter

Pharmacokinetics involves rate processes. Rate process are readily described with differential equations. With a diagram for a pharmacokinetic model with its circles and arrows you should now be able to write the corresponding differential equations. Thse differential eqautions can be integrated analytical by various methods. We have used the Laplace transform method as it can be applied to many of the equations found in pharmacokinetics. There are a few types of differential equations which can't be integrated and often it is just easier to let the computer do the integration for you. The computer takes the slope or rate of change or differential equation for a component and a starting point to get to a new value. Euler's method is a simple point and slope method that is relatively easy to understand. We will start by exploring this method in some detail before moving on to some other, more efficient methods.

These methods include

return to the Course index

This page was last modified: Tuesday, 24th Oct 2017 at 5:51 pm

Privacy Statement - 25 May 2018

Material on this website should be used for Educational or Self-Study Purposes Only

iBook and pdf versions of this material and other PK material is available

Copyright © 2001-2018 David W. A. Bourne (