# Calculation of Drug Concentration

## Uniform Multiple IV Bolus Dose Regimen

A patient is started on a drug at an IV bolus dose of 25 mg every 4 hours. Calculate the drug concentration at a few of time points during the first three dosing interval. Specifically calculate the concentration three hours after the first dose, two hours after the second dose and one hour after the third dose.
Assume a one compartment linear model applies to this drug in this concentration range.
The half-life and V for this drug in this patient (93.8 kg) are 1.9 hr and 0.07 L/kg, respectively.

NOTE: Clicking the button above

will prevent you getting credit for this problem

Print this page if you want, work the problems and

You will have one chance to submit your answers for this problem [# 1530834485]. You can try the homework problem more than once with different data to improve your grade. Your highest score is recorded. After submitting your answers you can use the browser back arrow to get back here and see how the compuer worked the problem.

**The equation:**

**Equation 25.2.1 Drug Concentration, Cp, after Multiple IV Bolus Doses (Uniform Dosing Interval and Dose)**

Last update: Sun 21 Apr 2019 08:03:56 pm

Privacy Statement - 25 May 2018

Material on this website should be used for Educational or Self-Study Purposes Only

iBook and pdf versions of this material and other PK material is available

Copyright © 2002-2020 David Bourne (david@boomer.org)