Drug Response versus Concentration

Concentration	Response Drug 1	Response Drug 2
0.0001	0.000448	0.00025
0.001	0.00448	0.0025
0.01	0.0448	0.025
0.1	0.446	0.249
1	4.26	2.44
10	29.9	20
100	74.6	71.4
1000	87.8	96.2
10000	89.4	99.6

Two drugs were tested for pharmacological response over a wide range of concentrations. The data collected are shown in the table above and the figure below. Estimate the Emax and EC_50% for each drug. Which one is more potent?

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The Equation:

Response equation

Equation for Response versus Concentration

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