Drug Response versus Concentration

Concentration	Response Drug 1	Response Drug 2
0.0001	0.000476	0.00019
0.001	0.00476	0.0019
0.01	0.0476	0.019
0.1	0.474	0.19
1	4.54	1.86
10	31.8	15.2
100	79.4	54.3
1000	93.4	73.1
10000	95.1	75.8

Two drugs were tested for pharmacological response over a wide range of concentrations. The data collected are shown in the table above and the figure below. Estimate the Emax and EC_50% for each drug. Which one is more potent?

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The Equation:

Response equation

Equation for Response versus Concentration

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