Drug Response versus Concentration

Concentration	Response Drug 1	Response Drug 2
0.0001	0.00258	0.00129
0.001	0.0258	0.0129
0.01	0.258	0.129
0.1	2.52	1.27
1	20.5	11.4
10	72.1	56.3
100	96.3	92.8
1000	99.6	99.2
10000	100	99.9

Two drugs were tested for pharmacological response over a wide range of concentrations. The data collected are shown in the table above and the figure below. Estimate the Emax and EC_50% for each drug. Which one is more potent?

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The Equation:

Response equation

Equation for Response versus Concentration

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