Drug Response versus Concentration

Concentration	Response Drug 1	Response Drug 2
0.0001	0.000381	0.000125
0.001	0.00381	0.00125
0.01	0.0381	0.0125
0.1	0.379	0.125
1	3.63	1.22
10	25.4	10
100	63.5	35.7
1000	74.7	48.1
10000	76.1	49.8

Two drugs were tested for pharmacological response over a wide range of concentrations. The data collected are shown in the table above and the figure below. Estimate the Emax and EC_50% for each drug. Which one is more potent?

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The Equation:

Response equation

Equation for Response versus Concentration

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