Drug Response versus Concentration

Concentration	Response Drug 1	Response Drug 2
0.0001	0.000419	0.000131
0.001	0.00419	0.00131
0.01	0.0419	0.0131
0.1	0.417	0.13
1	4	1.27
10	28	10.4
100	69.9	37.3
1000	82.3	50.2
10000	83.7	52

Two drugs were tested for pharmacological response over a wide range of concentrations. The data collected are shown in the table above and the figure below. Estimate the Emax and EC_50% for each drug. Which one is more potent?

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The Equation:

Response equation

Equation for Response versus Concentration

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