Drug Response versus Concentration

Concentration Response
Drug 1
Response
Drug 2
0.0001 0.000524 0.000395
0.001 0.00524 0.00395
0.01 0.0524 0.0395
0.1 0.52 0.394
1 4.86 3.8
10 29.3 28.3
100 58.9 79.8
1000 65.5 97.5
10000 66.2 99.7

Two drugs were tested for pharmacological response over a wide range of concentrations. The data collected are shown in the table above and the figure below. Estimate the Emax and EC50% for each drug. Which one is more potent?

The image

To see the Answers Click Here. Close the new window to return to this page.

The Equation:

Response equation

Equation for Response versus Concentration


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