Drug Response versus Concentration

Concentration	Response Drug 1	Response Drug 2
0.0001	0.000524	0.000395
0.001	0.00524	0.00395
0.01	0.0524	0.0395
0.1	0.52	0.394
1	4.86	3.8
10	29.3	28.3
100	58.9	79.8
1000	65.5	97.5
10000	66.2	99.7

Two drugs were tested for pharmacological response over a wide range of concentrations. The data collected are shown in the table above and the figure below. Estimate the Emax and EC_50% for each drug. Which one is more potent?

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The Equation:

Response equation

Equation for Response versus Concentration

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