Drug Response versus Concentration

Concentration	Response Drug 1	Response Drug 2
0.0001	0.000445	0.000246
0.001	0.00444	0.00246
0.01	0.0444	0.0246
0.1	0.442	0.246
1	4.2	2.39
10	27.9	19
100	64.1	62.1
1000	73.7	80.3
10000	74.8	82.7

Two drugs were tested for pharmacological response over a wide range of concentrations. The data collected are shown in the table above and the figure below. Estimate the Emax and EC_50% for each drug. Which one is more potent?

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The Equation:

Response equation

Equation for Response versus Concentration

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