Drug Response versus Concentration

Concentration Response
Drug 1
Response
Drug 2
0.0001 0.00726 0.00359
0.001 0.0726 0.0359
0.01 0.719 0.357
0.1 6.64 3.43
1 37.4 24.3
10 69.6 62.5
100 76.2 74.1
1000 76.9 75.5
10000 77 75.7

Two drugs were tested for pharmacological response over a wide range of concentrations. The data collected are shown in the table above and the figure below. Estimate the Emax and EC50% for each drug. Which one is more potent?

The image

To see the Answers Click Here. Close the new window to return to this page.

The Equation:

Response equation

Equation for Response versus Concentration


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