Drug Response versus Concentration

Concentration	Response Drug 1	Response Drug 2
0.0001	0.000389	0.000225
0.001	0.00389	0.00225
0.01	0.0389	0.0225
0.1	0.387	0.224
1	3.7	2.2
10	25.9	18
100	64.8	64.3
1000	76.3	86.6
10000	77.6	89.7

Two drugs were tested for pharmacological response over a wide range of concentrations. The data collected are shown in the table above and the figure below. Estimate the Emax and EC_50% for each drug. Which one is more potent?

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The Equation:

Response equation

Equation for Response versus Concentration

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