Drug Response versus Concentration

Concentration	Response Drug 1	Response Drug 2
0.0001	0.000887	0.000787
0.001	0.00886	0.00787
0.01	0.0885	0.0787
0.1	0.871	0.78
1	7.53	7.23
10	32	41.7
100	47.3	79.8
1000	49.7	87.8
10000	50	88.6

Two drugs were tested for pharmacological response over a wide range of concentrations. The data collected are shown in the table above and the figure below. Estimate the Emax and EC_50% for each drug. Which one is more potent?

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The Equation:

Response equation

Equation for Response versus Concentration

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