Drug Response versus Concentration

Concentration Response
Drug 1
Response
Drug 2
0.0001 0.00885 0.00221
0.001 0.0884 0.0221
0.01 0.877 0.22
0.1 8.13 2.12
1 46.9 15.3
10 89.8 40.8
100 98.9 48.9
1000 99.9 49.9
10000 100 50

Two drugs were tested for pharmacological response over a wide range of concentrations. The data collected are shown in the table above and the figure below. Estimate the Emax and EC50% for each drug. Which one is more potent?

The image

To see the Answers Click Here. Close the new window to return to this page.

The Equation:

Response equation

Equation for Response versus Concentration


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