Chapter 9

Calculation of Bioavailability Parameters

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Bioavailability Calculations

Student Objectives for this Chapter

After completing the material in this chapter each student should:- On many occasions you will be able to get the parameter values from tables and references. However, you should also know how to get these values from the data. The two parameters we will concentrate on in this Chapter are ka and F. These values can be used to compare dosage forms or brands. In Chapter 8 we saw the effect changing ka or F has on the plasma concentration time curve. In this chapter we will calculate ka and F from drug concentration versus time data.

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