Boomer Manual and Download
PharmPK Listserv and other PK Resources
Previous Page Course Index Next Page

Identifiability

Student Objectives for this Chapter

In the previous Chapter we considered the selection of the best model. We were able to compare model using the results from analysis using non-linear regression programs. If the model is too big, too many parameters, then we expect increased uncertainty in the parameter values determined by the program. It is possible to build model that are big enough that some parameters values can not be determined at all. These parameters can be called non identifiable. Parameters that can be determined, even if with some considerable variability, are essentially identifiable.

This topic will be discussed by considering definitions, some examples, and numerical and analytical techniques that can be used to explore the identifiability of model parameters.


return to the Course index


This page was last modified: Sunday, 28th Jul 2024 at 5:04 pm


Privacy Statement - 25 May 2018

iBook and pdf versions of this material and other PK material is available

Copyright © 2001-2022 David W. A. Bourne (david@boomer.org)