Multiple IV Bolus - Example Calculations 1
A potent drug is to be given by multiple IV bolus injections. On consideration of the patient's clinical condition it is decided that drug concentrations should be maintained between 6 and 0.5 mg/L. Assume a one compartment linear model applies to this drug in this concentration range.
The half-life and V for this drug in this patient are 2.9 hr and 33.9 L, respectively.
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