A previous study with Drug9 resulted in the following data.
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Equation 27.1.1 Elimination rate constant calculated from creatinine clearance
Equation 27.1.2 Creatinine Clearance calculated from a timed urine collection
UCr is the concentration of creatinine in urine in mg/dl, Vu is the volume of urine in ml, SCr is the serum creatinine concentration in mg/dl and t is the collection time in minutes.
Equation 27.1.3 Cockcroft and Gault equation for estimating Creatinine Clearance
Weight in kg and SCr is the serum creatinine concentration in mg/dl. Note, you should only multiply by 0.85 in the case of female patients. The original authors of this equation used actual body weight in Equation 27.1.3. More recently it has been recommended that ideal body (IBW) be used in this equation unless the actual body weight (ABW) is less. (Murphy, 2001, p4).
IBW (male) (kg) = 50 + 2.3 x (Ht(in) - 60) or IBW (female) (kg) = 45.5 + 2.3 x (Ht(in) - 60) (Murphy, 2001, p4-5)
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