A 81 year old male is admitted to the hospital with sepsis secondary to a UTI with gram-negative organisms seen on gram stain of urine. His admission weight is 179 lbs, and he is 5' 6" tall. He has chronic renal insufficiency which is stable with an admission serum creatinine of 2.332 mg/dl. The physician decides to start gentamicin and wants to obtain peak serum concentrations of 7 mg/L and trough serum concentrations of 1 mg/L or less. Assume a volume of distribution of 0.25 L/kg based on dosing weight. Based on your knowledge of estimation of creatinine clearance and gentamicin elimination rate constant [kel (hr

will prevent you getting credit for this problem

You will have one chance to submit your answers for this problem [# 1140757512]. You can try the homework problem more than once with different data to improve your grade. Your highest score is recorded. After submitting your answers you can use the browser back arrow to get back here and see how the compuer worked the problem.

Equation 27.4.1 IBW for Male Patients

Equation 27.4.2 IBW for Female Patients

Equation 27.4.3 Creatinine Clearance (Cockcroft-Gault Equation)

Equation 27.4.4 Dosing Interval, τ

Equation 27.4.5 Maintenance Dose

Equation 27.4.6 Loading Dose

Last update: Sat 20 Apr 2019 05:47:18 pm