Timehr |
Cpmg/L |
ΔAUCmg.hr/L |
AUCmg.hr/L |
Cp • tmg.hr/L |
ΔAUMCmg.hr ^{2}/L |
AUMCmg.hr ^{2}/L |

0 | 2.11 | 0 | 0 | 0 | 0 | 0 |

0.25 | 1.48 | 0.449 | 0.449 | 0.37 | 0.0463 | 0.0463 |

0.5 | 1.18 | 0.333 | 0.781 | 0.59 | 0.12 | 0.166 |

0.75 | 1.04 | 0.278 | 1.06 | 0.78 | 0.171 | 0.338 |

1 | 0.963 | A | C | 0.963 | 0.218 | 0.555 |

1.25 | 0.917 | B | 1.54 | 1.15 | 0.264 | 0.819 |

1.5 | 0.885 | 0.225 | 1.77 | 1.33 | D | F |

2 | 0.837 | 0.431 | 2.2 | 1.67 | E | 1.88 |

4 | 0.691 | 1.53 | 3.73 | 2.76 | 4.44 | 6.32 |

6 | 0.571 | 1.26 | 4.99 | 3.43 | 6.19 | 12.5 |

9 | 0.429 | 1.5 | 6.49 | 3.86 | 10.9 | 23.4 |

12 | 0.323 | 1.13 | 7.62 | 3.88 | 11.6 | 35 |

24 | 0.103 | 2.56 | 10.2 | 2.47 | 38.1 | 73.1 |

Infinity | 0 | G | H | 0 | I | J |

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**Equation 30.4.1 AUC for the segment from i-1 to i**

**Equation 30.4.2 AUC for the last segment from t _{last} to infinity**

where k' is the slowest rate constant. k' can be calculated from the terminal slope of Cp versus time on semi-log graph paper.

**Equation 30.4.3 AUMC for the last segment from t _{last} to infinity**

where k' is the slowest rate constant. k' can be calculated from the terminal slope of **Cp versus time** on semi-log graph paper.

**Equation 30.4.4 Mean Resident Time (MRT)**

**Equation 30.4.5 Clearance (CL)**

**Equation 30.4.6 Steady State Apparent Volume of Distribution, V _{ss}**

Last update: Sat 28 Nov 2015 09:52:07 am