Timehr |
Cpmg/L |
ΔAUCmg.hr/L |
AUCmg.hr/L |
Cp • tmg.hr/L |
ΔAUMCmg.hr ^{2}/L |
AUMCmg.hr ^{2}/L |

0 | 1.74 | 0 | 0 | 0 | 0 | 0 |

0.25 | 1.18 | 0.365 | 0.365 | 0.295 | 0.0369 | 0.0369 |

0.5 | 0.905 | 0.261 | 0.626 | 0.453 | 0.0934 | 0.13 |

0.75 | 0.76 | 0.208 | 0.834 | 0.57 | 0.128 | 0.258 |

1 | 0.679 | A | C | 0.679 | 0.156 | 0.414 |

1.25 | 0.63 | B | 1.18 | 0.788 | 0.183 | 0.598 |

1.5 | 0.597 | 0.153 | 1.33 | 0.896 | D | F |

2 | 0.549 | 0.287 | 1.62 | 1.1 | E | 1.31 |

4 | 0.417 | 0.966 | 2.58 | 1.67 | 2.77 | 4.07 |

6 | 0.318 | 0.735 | 3.32 | 1.91 | 3.58 | 7.65 |

9 | 0.212 | 0.795 | 4.11 | 1.91 | 5.72 | 13.4 |

12 | 0.141 | 0.53 | 4.64 | 1.69 | 5.4 | 18.8 |

24 | 0.0277 | 1.01 | 5.65 | 0.665 | 14.1 | 32.9 |

Infinity | 0 | G | H | 0 | I | J |

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**Equation 30.4.1 AUC for the segment from i-1 to i**

**Equation 30.4.2 AUC for the last segment from t _{last} to infinity**

where k' is the slowest rate constant. k' can be calculated from the terminal slope of Cp versus time on semi-log graph paper.

**Equation 30.4.3 AUMC for the last segment from t _{last} to infinity**

where k' is the slowest rate constant. k' can be calculated from the terminal slope of **Cp versus time** on semi-log graph paper.

**Equation 30.4.4 Mean Resident Time (MRT)**

**Equation 30.4.5 Clearance (CL)**

**Equation 30.4.6 Steady State Apparent Volume of Distribution, V _{ss}**

Last update: Sat 28 Nov 2015 09:52:07 am