Timehr |
Cpmg/L |
ΔAUCmg.hr/L |
AUCmg.hr/L |
Cp • tmg.hr/L |
ΔAUMCmg.hr ^{2}/L |
AUMCmg.hr ^{2}/L |

0 | 0.824 | 0 | 0 | 0 | 0 | 0 |

0.25 | 0.54 | 0.171 | 0.171 | 0.135 | 0.0169 | 0.0169 |

0.5 | 0.413 | 0.119 | 0.29 | 0.207 | 0.0427 | 0.0596 |

0.75 | 0.354 | 0.0959 | 0.386 | 0.266 | 0.059 | 0.119 |

1 | 0.326 | A | C | 0.326 | 0.0739 | 0.193 |

1.25 | 0.31 | B | 0.55 | 0.388 | 0.0892 | 0.282 |

1.5 | 0.3 | 0.0763 | 0.626 | 0.45 | D | F |

2 | 0.287 | 0.147 | 0.773 | 0.574 | E | 0.642 |

4 | 0.247 | 0.534 | 1.31 | 0.988 | 1.56 | 2.2 |

6 | 0.213 | 0.46 | 1.77 | 1.28 | 2.27 | 4.47 |

9 | 0.171 | 0.576 | 2.34 | 1.54 | 4.23 | 8.7 |

12 | 0.137 | 0.462 | 2.81 | 1.64 | 4.77 | 13.5 |

24 | 0.057 | 1.16 | 3.97 | 1.37 | 18.1 | 31.5 |

Infinity | 0 | G | H | 0 | I | J |

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**Equation 30.4.1 AUC for the segment from i-1 to i**

**Equation 30.4.2 AUC for the last segment from t _{last} to infinity**

where k' is the slowest rate constant. k' can be calculated from the terminal slope of Cp versus time on semi-log graph paper.

**Equation 30.4.3 AUMC for the last segment from t _{last} to infinity**

where k' is the slowest rate constant. k' can be calculated from the terminal slope of **Cp versus time** on semi-log graph paper.

**Equation 30.4.4 Mean Resident Time (MRT)**

**Equation 30.4.5 Clearance (CL)**

**Equation 30.4.6 Steady State Apparent Volume of Distribution, V _{ss}**

Last update: Sun 28 Apr 2019 01:41:39 am

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