Timehr |
Cpmg/L |
ΔAUCmg.hr/L |
AUCmg.hr/L |
Cp • tmg.hr/L |
ΔAUMCmg.hr ^{2}/L |
AUMCmg.hr ^{2}/L |

0 | 1.1 | 0 | 0 | 0 | 0 | 0 |

0.25 | 0.697 | 0.225 | 0.225 | 0.174 | 0.0218 | 0.0218 |

0.5 | 0.508 | 0.151 | 0.375 | 0.254 | 0.0535 | 0.0753 |

0.75 | 0.416 | 0.116 | 0.491 | 0.312 | 0.0708 | 0.146 |

1 | 0.368 | A | C | 0.368 | 0.085 | 0.231 |

1.25 | 0.341 | B | 0.677 | 0.426 | 0.0993 | 0.33 |

1.5 | 0.322 | 0.0829 | 0.76 | 0.483 | D | F |

2 | 0.296 | 0.155 | 0.915 | 0.592 | E | 0.713 |

4 | 0.222 | 0.518 | 1.43 | 0.888 | 1.48 | 2.19 |

6 | 0.167 | 0.389 | 1.82 | 1 | 1.89 | 4.08 |

9 | 0.109 | 0.414 | 2.24 | 0.981 | 2.97 | 7.06 |

12 | 0.0715 | 0.271 | 2.51 | 0.858 | 2.76 | 9.82 |

24 | 0.013 | 0.507 | 3.01 | 0.312 | 7.02 | 16.8 |

Infinity | 0 | G | H | 0 | I | J |

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**Equation 30.4.1 AUC for the segment from i-1 to i**

**Equation 30.4.2 AUC for the last segment from t _{last} to infinity**

where k' is the slowest rate constant. k' can be calculated from the terminal slope of Cp versus time on semi-log graph paper.

**Equation 30.4.3 AUMC for the last segment from t _{last} to infinity**

where k' is the slowest rate constant. k' can be calculated from the terminal slope of **Cp versus time** on semi-log graph paper.

**Equation 30.4.4 Mean Resident Time (MRT)**

**Equation 30.4.5 Clearance (CL)**

**Equation 30.4.6 Steady State Apparent Volume of Distribution, V _{ss}**

Last update: Sat 28 Nov 2015 09:52:07 am