Timehr |
Cpmg/L |
ΔAUCmg.hr/L |
AUCmg.hr/L |
Cp • tmg.hr/L |
ΔAUMCmg.hr ^{2}/L |
AUMCmg.hr ^{2}/L |

0 | 4.94 | 0 | 0 | 0 | 0 | 0 |

0.25 | 3.17 | 1.01 | 1.01 | 0.793 | 0.0991 | 0.0991 |

0.5 | 2.45 | 0.703 | 1.72 | 1.23 | 0.252 | 0.351 |

0.75 | 2.13 | 0.573 | 2.29 | 1.6 | 0.353 | 0.704 |

1 | 1.97 | A | C | 1.97 | 0.446 | 1.15 |

1.25 | 1.87 | B | 3.28 | 2.34 | 0.538 | 1.69 |

1.5 | 1.79 | 0.458 | 3.74 | 2.69 | D | F |

2 | 1.67 | 0.865 | 4.6 | 3.34 | E | 3.82 |

4 | 1.27 | 2.94 | 7.54 | 5.08 | 8.42 | 12.2 |

6 | 0.968 | 2.24 | 9.78 | 5.81 | 10.9 | 23.1 |

9 | 0.643 | 2.42 | 12.2 | 5.79 | 17.4 | 40.5 |

12 | 0.428 | 1.61 | 13.8 | 5.14 | 16.4 | 56.9 |

24 | 0.0838 | 3.07 | 16.9 | 2.01 | 42.9 | 99.8 |

Infinity | 0 | G | H | 0 | I | J |

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**Equation 30.4.1 AUC for the segment from i-1 to i**

**Equation 30.4.2 AUC for the last segment from t _{last} to infinity**

where k' is the slowest rate constant. k' can be calculated from the terminal slope of Cp versus time on semi-log graph paper.

**Equation 30.4.3 AUMC for the last segment from t _{last} to infinity**

where k' is the slowest rate constant. k' can be calculated from the terminal slope of **Cp versus time** on semi-log graph paper.

**Equation 30.4.4 Mean Resident Time (MRT)**

**Equation 30.4.5 Clearance (CL)**

**Equation 30.4.6 Steady State Apparent Volume of Distribution, V _{ss}**

Last update: Sat 28 Nov 2015 09:52:07 am