Timehr |
Cpmg/L |
ΔAUCmg.hr/L |
AUCmg.hr/L |
Cp • tmg.hr/L |
ΔAUMCmg.hr ^{2}/L |
AUMCmg.hr ^{2}/L |

0 | 9.7 | 0 | 0 | 0 | 0 | 0 |

0.25 | 6.92 | 2.08 | 2.08 | 1.73 | 0.216 | 0.216 |

0.5 | 5.65 | 1.57 | 3.65 | 2.83 | 0.569 | 0.786 |

0.75 | 5.06 | 1.34 | 4.99 | 3.8 | 0.828 | 1.61 |

1 | 4.76 | A | C | 4.76 | 1.07 | 2.68 |

1.25 | 4.6 | B | 7.39 | 5.75 | 1.31 | 4 |

1.5 | 4.5 | 1.14 | 8.52 | 6.75 | D | F |

2 | 4.36 | 2.22 | 10.7 | 8.72 | E | 9.43 |

4 | 3.93 | 8.29 | 19 | 15.7 | 24.4 | 33.9 |

6 | 3.55 | 7.48 | 26.5 | 21.3 | 37 | 70.9 |

9 | 3.06 | 9.92 | 36.4 | 27.5 | 73.3 | 144 |

12 | 2.63 | 8.54 | 45 | 31.6 | 88.7 | 233 |

24 | 1.44 | 24.4 | 69.4 | 34.6 | 397 | 630 |

Infinity | 0 | G | H | 0 | I | J |

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**Equation 30.4.1 AUC for the segment from i-1 to i**

**Equation 30.4.2 AUC for the last segment from t _{last} to infinity**

where k' is the slowest rate constant. k' can be calculated from the terminal slope of Cp versus time on semi-log graph paper.

**Equation 30.4.3 AUMC for the last segment from t _{last} to infinity**

where k' is the slowest rate constant. k' can be calculated from the terminal slope of **Cp versus time** on semi-log graph paper.

**Equation 30.4.4 Mean Resident Time (MRT)**

**Equation 30.4.5 Clearance (CL)**

**Equation 30.4.6 Steady State Apparent Volume of Distribution, V _{ss}**

Last update: Sat 28 Nov 2015 09:52:07 am