Laplace Transform Examples

One Compartment Model

Oral Dose Administration with Metabolism to Active Drug

Derive the Integrated Equation for the Amount of Metabolite in the Body, X4

The Model

Model with X3 highlighted

Component of Interest - Metabolite in the Body

Step 1. Write the differential equations
Step 2. Transform into the Laplace domain
Step 3. Rearrange and solve for L(X3)
Step 4. Back transform to produce the integrated equation for X1

All the steps

Return to Index

return to the Course index

This page was last modified: Wednesday, 8th Nov 2017 at 5:38 pm

Privacy Statement - 25 May 2018

Material on this website should be used for Educational or Self-Study Purposes Only

iBook and pdf versions of this material and other PK material is available

Copyright © 2001-2019 David W. A. Bourne (