Chapter 12 Physical-Chemical Factors Affecting Oral Absorption

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Physical-Chemical Factors Affecting Oral Absorption

Student Objectives for this Chapter

After completing the material in this chapter each student should:-

be able to describe the physical-chemical factors that affects oral absorption
be able to describe the pH-partition hypothesis as it applies to drug absorption and estimates values of Brodies D value
be able to describe Fick's first law as it applies to drug dissolution

There are two major headings, which can be used to discuss this material as it affect oral drug absorption. These are:

the pH-partition theory and
the dissolution of drugs.

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