4. After an I.V. bolus dose of 500 mg the data collected in Table IV-3 were collected.
Time (hr) | 1 | 2 | 3 | 4 | 6 | 8 | 10 |
Cp (mcg/ml) | 72 | 51 | 33 | 20 | 14 | 9 | 4 |
Plot the data on semi-log graph paper (Figure IV-6) and determine Cp1, Cp2, t1 and t2.
Figure IV-6. Plot of Cp Versus Time on Semi-log Graph Paper After an I.V. Bolus Dose of 500 mg.
Use drug specific parameter values to estimate concentration versus time plots
Copyright 2002 David W.A. Bourne